NL-OMON44893已完成不适用
Cerebral perfusion in patients with severe aortic valve stenosis undergoing aortic valve replacement. - Cerebral perfusion in patients with severe aortic valve stenosis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 95
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99(—)
入选标准
- •Cohort A (N<=30):
- •* Age between 50-75 years
- •* Presence of aortic stenosis (aortic valve area less than 1 cm2)
- •* Eligible for a surgical aortic valve replacement (AVR)
- •* Expected aortic valve size of 23-25 mm;Cohort B (N<=30):
- •Age between 50-95 years
- •* Presence of aortic stenosis (aortic valve area less than 1 cm2)
- •* Eligible for transcatheter aorta valve implantation (TAVI)
排除标准
- •* Additional complex surgical procedures indicated (e.g. restoration of aortic root)
- •* Medical history of neurological disease, active malignant disease/ cardio- toxic treatment and/or venous insufficiency
- •* Contraindication to MRI exposure (*vragenlijst MRI onderzoek*)
- •* Smoking or having smoked less than 10 years ago;Cohort B:
- •* Medical history neurological disease, active malignant disease/ cardio- toxic treatment and/or venous insufficiency
- •* Contraindication to MRI exposure (*vragenlijst MRI onderzoek*)
研究者
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