A Before After Comparison of the Effectiveness of a Community-based Salt Reduction Program Done in Lithgow, Australia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 991
- 试验地点
- 2
- 主要终点
- Urinary sodium excretion (mmol/l)
研究概览
简要总结
The objective of this study is to determine whether a community-based salt reduction program can reduce average salt consumption levels. Baseline levels of salt consumption were measured in 2011, the salt reduction program was then implemented, and now in 2014 investigators are remeasuring salt consumption levels in the community. The hypothesis investigators are testing is that the salt reduction program will have led to a change in salt consumption levels between 2011 and 2014. The study is being done in Lithgow, a regional town in New South Wales , Australia.
详细描述
The primary objective of this project is to determine whether there have been changes in average salt consumption levels in the Lithgow population from 2011 to 2014. The primary null hypothesis to be tested is that there will be no difference between the mean 24-hour urinary sodium excretion levels between 2011 and 2014.
The sample of 419 individuals with 24-hour urine samples in the baseline survey and 600 individuals in the follow-up survey will provide 80% power to detect a difference of 0.7 g/day salt between the mean levels of excretion before and after the intervention. There will be more than 95% power to detect a difference of 1.0 g/day salt or greater.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All adults over the age of 20 years residing in the Lithgow area are eligible
- •No exclusion based on inter-current illness, use of medications or any other aspect of demography or personal history.
排除标准
- 未提供
结局指标
主要结局
Urinary sodium excretion (mmol/l)
时间窗: up to 4 years
A single 24-hour urine collection will be obtained with the first voided urine upon waking on the day of collection being discarded and participants then collecting all voided urine up to and including the first void the following morning. The times at the beginning and the end of urine collection are recorded.
次要结局
- Sources of sodium(up to 4 years)
- Knowledge, attitudes and behaviors towards salt intake(up to 4 years)
研究者
Professor Bruce Neal
Professor
The George Institute