Mechano-physiological Approach to Normal Anorectal Function and the Classification of Defecatory Disorders
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 17
- 试验地点
- 1
- 主要终点
- change in shape of anorectum during changes in intraabdominal pressure and defecation
研究概览
简要总结
We hypothesize that defecatory disorders can be described in mechanical terms which would allow a mechanistic description of disorders which would in turn allow better directed biofeedback mechanisms to treat disorders of defecation.
详细描述
Disorders of defecation are very common and the process of defecation remains poorly described. This results in a limited approach to treatment of patients, with limited success. This study will simultaneously measure multiple components of the process of defecation - the abdominal wall and perineal muscle activity, the pressure within the rectum and in the anal canal and the change in shape of the anorectal region of the colon, in order to develop a biomechanical model which can describe the normal and abnormal defecatory process. It is anticipated that, by understanding the process in these terms will allow a new approach to categorizing and describing defecation problems which in turn will lead to more specific approaches of treatment which will be tailored to individual patients. These parameters will compared in volunteers with no defecatory disorders and patients with defecatory disorders who are being referred for defecography as part of their clinical evaluation.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •No defecatory problems
- •On no medication which affect bowel habits
排除标准
- •Pregnancy
- •Inclusion Criteria:
- •Difficulty in defecation
- •Exclusion criteria:
- •Pregnancy
- •Medication which can affect bowel movement
结局指标
主要结局
change in shape of anorectum during changes in intraabdominal pressure and defecation
时间窗: start of anorectal manometry procedure until procedure end
measure change in dimension over time
次要结局
未报告次要终点
