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临床试验/NCT05076331
NCT05076331Unknown不适用

Health and Aging Brain Study: Health Disparities Tau PET Scan Study

University of North Texas Health Science Center1 个研究点 分布在 1 个国家目标入组 3,000 人开始时间: 2021年4月20日最近更新:
适应症

试验速览

阶段
不适用
入组人数
3,000
试验地点
1
主要终点
Health Disparities in Aging

研究概览

简要总结

The purpose of this project is to study the aging brain among participants enrolled in the Health and Aging Brain Study: Health Disparities project . There are a number of things that can influence how people think as they age, including diabetes, depression, as well as our biology. In this study, the investigators seek to study the aging brain by using brain PET scans that create detailed pictures of the brain.

详细描述

There are a number of things that can influence how we think as people age, including diabetes, depression, as well as our biology. In this study, the investigators are using PET scans with a tracer to create detailed pictures of the brain. This information will be used to help the investigators understand how the brain ages and in the future could be used to develop better diagnostics and treatments for Alzheimer's disease and memory loss in Mexican Americans, African Americans, and non-Hispanic whites. The goal of this study is to address this disparity by enrolling ethnically diverse participants in this study.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
50 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Enrolled in the Health and Aging Brain Study HD: Health Disparities project
  • Provided consent to re-contact
  • Willing and capable of undergoing PET scan of the head

排除标准

  • Inability to provide informed consent by self or by proxy.
  • Pregnant or breast feeding women*
  • History of alcoholism or drug dependency/abuse within the last 2 years before screening
  • Hypersensitivity to the active substance or to any of the following excipients is contraindicated: sodium dihydrogen phosphate, phosphoric acid, sodium ascorbate, ethanol (anhydrous), water for injection
  • Participants may not be in this study if they do not meet the safety criteria to undergo imaging procedures.

结局指标

主要结局

Health Disparities in Aging

时间窗: Through study completion in 2 years

Examine the prevalence of Tau burden among a multi ethnic cohort

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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