NCT00130767Unknown4 期
Kinetics of the Finasteride Prostate Induced Apoptosis
适应症
相关药物
试验速览
- 阶段
- 4 期
- 入组人数
- 90
- 试验地点
- 2
- 主要终点
- Date of the maximum apoptosis in the prostate tissues treated by finasteride
研究概览
简要总结
The aim of this study is to evaluate the mechanisms involved in the apoptosis induced by a treatment of finasteride on benign prostate hyperplasia (BPH). Five sets of patients who need a surgical procedure because of low tract urinary symptoms are randomly attributed to one of five sets of treatment: 0, 7, 14, 21 or 28 days of finasteride treatment before the day of the procedure. Prostate histological fragments are conditioned for molecular and histologic studies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 90 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Patients with low tract urinary symptoms needing a surgical procedure
- •No previous treatment with finasteride
- •No androgen deficiency; no prostate cancer suspected.
排除标准
- 未提供
结局指标
主要结局
Date of the maximum apoptosis in the prostate tissues treated by finasteride
次要结局
- Molecular mechanisms involved in BPH finasteride induced apoptosis
- Decrease in the frequency of the hemorrhagic incidents after the surgical procedure in patients with a treatment using finasteride
研究者
研究点 (2)
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