The Effect of Adjunct Use of Diode Laser Therapy and Omega 3 Gel in Local Drug Delivery Approach on The Treatment of Localized Aggressive Periodontitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Pocket depth
研究概览
简要总结
This study aims to evaluate and compare the effect of combination therapy between diode laser and omega3 gel in the local drug delivery approach as an adjunct to scaling and root planning on the management of localized aggressive periodontitis clinically and immunologically.
详细描述
Periodontitis is a disease of the periodontium occurring in an otherwise healthy adolescent, which is characterized by a rapid loss of alveolar bone about more than one tooth of the permanent dentition.
The laser approach is an efficient and atraumatic technique to enhance its use for periodontal treatment. Within the limits of scientific data, treatment with diode laser and SRP showed a higher effect than SRP or laser alone.
Omega3 Polyunsaturated fatty acids (PUFA) have well recognized anti-inflammatory properties. They decrease inflammation through multiple pathways.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with localized aggressive periodontitis.
- •Patients must be medically free.
- •Optimal compliance as evidenced by no missed treatment appointments and a positive attitude to maintain oral hygiene.
- •Patients who are willing to participate in this study can enroll and complete it.
排除标准
- •Patients with generalized aggressive periodontitis. Patients are over 35 years old.
- •Pregnancy.
- •Patients had scaling and root planning or antibiotic therapy in the last 6 months.
- •Patients with hypersensitivity to fish oil.
研究组 & 干预措施
Group I
Thirteen sites [scaling-root planning (SRP)] were used as a control group.
干预措施: Scaling-root planning (SRP) (Procedure)
Group II
Thirteen sites [scaling-root planning (SRP)+ laser therapy with application of methyl cellulose gel at repeated times weekly for one month].
干预措施: Scaling-root planning (SRP)+ laser therapy (Procedure)
Group III
Thirteen sites [scaling-root planning (SRP) + omega 3 gel repeated time weekly for one month].
干预措施: Scaling-root planning (SRP)+ omega 3 gel (Procedure)
Group IV
Thirteen sites [combination therapy between scaling-root planning (SRP) + laser + omega 3 gel in repeated time weekly for one month].
干预措施: Scaling-root planning (SRP)+ laser therapy+ omega 3 gel (Procedure)
结局指标
主要结局
Pocket depth
时间窗: 6 months post-procedure
Probing pocket depth (PD) was recorded according to Ramfijord 1967.
次要结局
- Bleeding on probing(6 months post-procedure)
- Clinical attachment level loss(6 months post-procedure)
- Plaque score(6 months post-procedure)
研究者
Dalia Mohammed Elsayed Ghannam
Dentist at ministry of health
Tanta University