ACTRN12608000248369已完成3 期
The role of Gabapentin in the treatment of refractory chronic dry cough: A randomised double-blind placebo-controlled study.
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 56
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 80 Years（—）
- 性别
- All
入选标准
- •Persistent non-productive cough of more than 8 weeks duration,
- •Male or female between ages of 18 and 80 years,
- •Non-smoker or ex-smoker with less than 10 pack years,
- •To have been well during the 4 weeks prior to study entry,
- •Informed consent obtained.
排除标准
- •Productive cough,
- •Current smoker,
- •Smoking history >10 pack years,
- •Pregnancy/breast feeding,
- •Other respiratory disease, eg: bronchiectasis, COPD.
- •Inability to attend study visits
- •Respiratory tract infection during month prior to randomisation
- •Impaired liver function at Visit 1 as shown by Aspartate aminotransferase (AST), an enzyme normally present in liver and heart cells and alanine aminotransferase (ALT). If the liver is injured, the liver cells spill the enzymes into blood, raising the enzyme levels in the blood and signaling liver damage.
- •Therefore, an AST, ALT, alkaline phosphatase or total bilirubin greater than 2 times the upper limit of normal will exclude a participant.
研究者
相似试验
已完成
2 期
The efficacy of Gabapentin in the management of post menopausal sleep disorder and life qualitySleep disturbance.Nonorganic sleep disordersIRCT201304184686N3Arak University Medical of Sciences270
已完成
2 期
The use of gabapentin in the treatment ofkeratoconusPostoperative painC23.550.767.700RBR-23r5mcniversidade do Oeste de Santa Catarina
已完成
不适用
A study to evaluate the usefulness of drug Gabapentin in reducing adverse symptoms after brain injuryCTRI/2020/04/024537DR SURUCHI60
尚未招募
3 期
The efficacy of Gabapentin in chronic refractory cough in Interstitial Lung DiseaseCTRI/2024/07/071040one
招募中
4 期
Gabapentin as symptomatic therapy of cerebellar ataxia in degenerative and inflammatory CNS-diseaseG11.2G31.9G35Late-onset cerebellar ataxiaDegenerative disease of nervous system, unspecifiedMultiple sclerosisDRKS00000269FakultätsleitungCharité - Universitätsmedizin Berlin72