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临床试验/NCT04379310
NCT04379310已完成不适用

Evaluation of Demographic and Clinical Parameters on Admission and Medications Used for Comorbidities in Patients With Covid-19 Pneumonia: A Single Center Experience in Turkey

Istanbul Nisantasi University1 个研究点 分布在 1 个国家目标入组 54 人开始时间: 2020年5月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
54
试验地点
1
主要终点
oxygen saturation on admission

研究概览

简要总结

Investigators will recruit patients diagnosed with COVID-19 pneumonia between March 11th, 2020 and April 15th, 2020 in emergency, internal medicine and cardiology outpatient clinics, retrospectively and analyze their clinical and demographic features on admission in regard to their medications used for chronic diseases regularly.

详细描述

Covid-19 infections demonstrated a pandemic spread after January 2020 and their associations with patient characteristics and comorbidities are intensely studied. Investigators also want to find out potential relations between major medications taken for chronic diseases and clinical parameters of patients with Covid-19 pneumonia.

For the study, investigators will recruit patients diagnosed with COVID-19 pneumonia between March 11th, 2020 (the date at which the first case of Covid-19 in Turkey officially declared) and April 15th, 2020 in emergency, internal medicine and cardiology outpatient clinics, retrospectively. All of the demographic features, complaints on admission, reports of computed tomography (CT) scans of the chest without intravenous contrast issued by the staff radiologist, c-reactive protein (CRP) and complete blood count (CBC) values on admission will be recorded retrospectively. Their polymerase chain reaction (PCR) test results will be derived from the hospital records based on public health covid-19 database notifications and list of medications taken regularly for more than 8 weeks before the diagnosis of COVID-19 pneumonia from the national pharmacy database. Information about other systemic diseases and major medical conditions of patients will be procured from the medical histories gained by relevant physicians. Patient taking each drug group will be compared to those not taking that drugs in terms of clinical and demographical features mentioned above. Statistical analysis will be performed by using SPSS software.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 99 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Covid-19 pneumonia at least with typical infiltration on CT +/- positive PCR.

排除标准

  • no typical infiltration and negative PCR results.
  • not newly diagnosed.

研究组 & 干预措施

covid-19 pneumonia

diagnosed with covid-19 by using PCR and computed tomography scans

干预措施: ACE Inhibitors and Calcium Channel Blockers (Drug)

结局指标

主要结局

oxygen saturation on admission

时间窗: 2 week

hypoxia

extend of lung involvement

时间窗: 1 week

number of segments involved on admission

次要结局

未报告次要终点

研究者

发起方
Istanbul Nisantasi University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Murat Civan

M.D.

Istanbul Nisantasi University

研究点 (1)

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