Hilotherapy for prevention of chemotherapy-induced peripheral polyneuropathy - A unicentric, prospective-controlled, randomized clinical trial for comparison of local hilotherapy vs. no therapy to prevent peripheral polyneuropathy during Taxan-based chemotherapy regimen - HiPPo

niversitätsklinikum Ulm0 个研究点目标入组 150 人开始时间: 2023年7月6日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•* Written consent for participation in this trail
•* Age =18 years
•* Breast or genital cancer of the woman
•* Planned application of a Taxan-based chemotherapy regimen (Paclitaxel, Nac-Paclitaxel) independent of the therapy line
•* Taxan- and Platin-naivity
•* Sufficient knowledge of the German language to assure an adequat survey of patient's history

•* pre-existing peripheral polyneuropathy
•chemotherapy with taxan- and/or carboplatin-based regimens in a preceding therapy
•Existence of one of the following diseases:
•> Diabetes mellitus (of any type)
•> neurological diseases that are involving peripheral nerve damage (Multiple Sclerosis, Amytrophic lateral sclerosis, Parkinson's disease)
•> chronic pain syndrome
•> Cryoglobulinemia
•> cold hemagglutination
•> cold hives / cold contact hives
•> Raynaud's disease
•> significant peripheral artery disease
•Lack of knowledge of German

发起方

niversitätsklinikum Ulm