Stromal Gene Expression During Pulmonary Sarcoidosis
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- To Identify Gene Expression Patterns That Specifically Correlate With Active Pulmonary Sarcoidosis.
研究概览
简要总结
to determine the genetic pathways operating at the tissue level to cause granulomatous inflammation in the lungs and lymph nodes of patients with sarcoidosis. By so doing, we hope to identify unique genetic mechanisms which will aid in the diagnosis of sarcoidosis and will help us understand the pathogenesis of this poorly understood disease.
详细描述
to collect small sample of lung tissue recovered from a clinical procedure such as bronchoscopy, or a mediastinoscopy (a procedure in which a lighted instrument (mediastinoscope) is inserted through a neck incision to visually examine the structures in the top of the chest cavity and to take a sample (biopsy) of tissue.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis of sarcoidosis
排除标准
- •inability to provide consent
结局指标
主要结局
To Identify Gene Expression Patterns That Specifically Correlate With Active Pulmonary Sarcoidosis.
时间窗: end of study
次要结局
- To Determine if Gene Expression Patterns Correlate With The Severity of Illness Of Sarcoidosis Patients(end of study)
研究者
Elliott Crouser MD
Associate Professor of Internal Medicine
Ohio State University