NCT01023282已完成1 期
Randomised, Double-blind, Placebo-controlled Study Evaluating Safety and Tolerability of ACR325 in Parkinson's Disease Patients, With Evaluation of the Effect on Levodopa Induced Dyskinesias as a Secondary Measure
NeuroSearch A/S2 个研究点 分布在 1 个国家目标入组 22 人开始时间: 2009年11月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 22
- 试验地点
- 2
- 主要终点
- Safety and tolerability
研究概览
简要总结
The study will evaluate the safety and tolerability of ACR325 in Parkinson disease patients and evaluate the effect on levodopa induced dyskinesias.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of idiopathic Parkinson"s disease according to the United Kingdom Parkinson's Disease Society brain bank diagnostic criteria
- •Levodopa induced dyskinesia
排除标准
- •Previous surgery for Parkinson's disease
- •Any current or history of heart condition or increased pro-arrhythmic risk
- •Severe or ongoing unstable medical condition
研究组 & 干预措施
ACR325
Experimental
干预措施: ACR325 (Drug)
Placebo
Placebo Comparator
干预措施: ACR325 (Drug)
Placebo
Placebo Comparator
干预措施: Placebo (Drug)
结局指标
主要结局
Safety and tolerability
时间窗: 4 weeks
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
相似试验
已完成
2 期
Study Assessing Efficacy and Safety of AKST4290 in Subjects With Parkinson's Disease on Stable Dopaminergic TreatmentParkinson DiseaseNCT04369430Alkahest, Inc.110
已完成
1 期
Safety and Tolerability Study of K0706 in Subjects With Parkinson's DiseaseParkinson DiseaseNCT02970019Sun Pharma Advanced Research Company Limited60
进行中（未招募）
2 期
Safety, Tolerability, Pharmacokinetics and Efficacy Study of Radotinib in Parkinson's DiseaseParkinson DiseaseNCT04691661Il-Yang Pharm. Co., Ltd.43
已完成
3 期
A Trial To Assess Switching From Ropinirole, Pramipexole Or Cabergoline To The Rotigotine Transdermal System In Idiopathic Parkinson's DiseaseParkinson's DiseaseNCT00242008UCB Pharma
已完成
4 期
The Effect of Donepezil on Gait and Balance in Parkinson's DiseaseParkinson's DiseaseNCT01521117Oregon Health and Science University21