Effects of intraoperative HES130/0.4 on postoperative kidney function :A retrospective cohort study using DPC database. - Effects of HES130/0.4 on postoperative kidney function
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 50,000
研究概览
简要总结
The incidence of any stages of postoperative acute kidney injury (AKI) was not different between HES group and non-HES group (6.2% vs. 5.5%; RR, 1.123; 95%CI, 0.999-1.263; P=0.053). The number of patients who required postoperative renal replacement therapy was significantly smaller in HES group than in non-HES group (0.2% vs. 0.4%; RR, 0.50; 95%CI, 0.28-0.90; P=0.02). The length of postoperative hospital stay was longer in HES group but 30-day mortality was not statistically different. The incidence of any stages of AKI was significantly lower in HES/non-Alb group than Alb/non-HES group. The patients in HES/non-Alb group had significantly shorter length of hospital stay and significantly low 30-day mortality than the patients in Alb/non-HES group.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •(1)Patients who underwent dialysis treatment or end stage kidney disease (eGFR<15mL/min/1.73m2) before surgery (2)Patients who received dextran or HES70/0.5 (3)Patients who received HES130/0.4 or albumin or blood products during the period between 7 days before surgery and the day of surgery (4)Patients who died within 2 days after surgery (5)Patients who underwent multiple surgeries (during the period of 30 days before and 30 days after the surgery) (6)Patients who received HES130/0.4 only before and/or after surgery on the day of surgery