Peripheral Refraction and Aberration in Myopic Progression and Myopic Control
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Changes in cycloplegic off-axial auto-refraction, aberration and eyeball length
研究概览
简要总结
The primary objective of the current study is to investigate changes in peripheral refraction and aberration in children wearing orthokeratology lenses and single-vision spectacles.
详细描述
Apart from being effective in reducing low to moderate myopia, orthokeratology has been shown to have potential in retarding myopic progression. The central cornea is flattened and peripheral optics altered in orthokeratology and it has been suggested that orthokeratology slows myopic progression through the alteration of peripheral optics. The aim of the current study is to investigate the changes in peripheral refraction and aberration in children wearing orthokeratology (study group) and single-vision spectacles (control group).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 9 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Myopia (refractive sphere): > 0.50D and ≤ 6.00D
- •Astigmatism: with-the-rule astigmatism (axes 180 +/- 30) ≤ 1.50D; astigmatism of other axes ≤ 0.50D
- •Spherical equivalent (SE): > 0.50D and ≤ 6.75D (myopia)
- •Best corrected monocular visual acuity: equal to or better than 6/7.5 in Snellen scale
- •Willingness to wear contact lenses or spectacles on a daily basis
- •Availability for follow-up for at least 2 years
排除标准
- •Strabismus at distance or near
- •Contraindication for contact lens wear and orthokeratology (e.g. limbus to limbus corneal cylinder and dislocated corneal apex)
- •Prior experience with the use of rigid lenses (including orthokeratology)
- •Prior experience with myopic control treatment (e.g. refractive therapy or progressive spectacles)
- •Systemic or ocular conditions which may affect contact lens wear (e.g. allergy and medication)
- •Systemic or ocular conditions which may affect refractive development (e.g. Down syndrome, ptosis)
结局指标
主要结局
Changes in cycloplegic off-axial auto-refraction, aberration and eyeball length
时间窗: 2 years
次要结局
未报告次要终点
研究者
Pauline Cho
Professor
The Hong Kong Polytechnic University