临床试验/NCT06533670

NCT06533670进行中（未招募）不适用

Tumor Microenvironment Alteration During Neoadjuvant Chemotherapy in HER2 Positive Breast Cancer Patients

Seoul National University Hospital1 个研究点分布在 1 个国家目标入组 30 人开始时间: 2024年7月19日最近更新: 2026年1月28日

适应症

试验速览

阶段: 不适用
状态: 进行中（未招募）
发起方: Seoul National University Hospital
入组人数: 30
试验地点: 1
主要终点: tumor microenvironment alteration

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Evaluate for changes in the tumor microenvironment before/during neoadjuvant chemotherapy and after treatment in patients diagnosed with HER2-positive advanced breast cancer and receiving neoadjuvant cancer therapy and surgery for curative purposes.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•i. Adult patients over 18 years of age ii. Patients undergoing curative treatment including neoadjuvant chemotherapy after confirmation of breast cancer without distant metastases iii. Clinical T stage II-IV patients iv. HER2 positive breast cancer patients

排除标准

•If you have other comorbidities that, according to the researcher's judgment, may affect the results of the study

结局指标

主要结局

tumor microenvironment alteration

时间窗: 6 months

tumor microenvironment changes during neoadjuvant chemotherapy (NAC) for HER2-positive breast cancer.

次要结局

未报告次要终点

研究者

发起方

Seoul National University Hospital

申办方类型

Other

责任方

Principal Investigator

主要研究者

Wonshik Han

Professor

Seoul National University Hospital

研究点 (1)

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