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临床试验/NCT07084857
NCT07084857已完成不适用

"Association Between Isokinetic Lower Extremity Muscle Strength and Bone Mineral Density in Elderly Women With and Without Osteoporosis: A Case-Control Study"

Cairo University1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2025年2月8日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
70
试验地点
1
主要终点
isokinetic strength of hip muscles

研究概览

简要总结

bone density and muscle strength appear to be more related to each other. Examining the association between muscle strength and bone health is very important in recognizing risk factors for lower extremity muscle weakness.

详细描述

Dual Energy X-ray Absorptiometry (DEXA) scan will be used to assess hip bone mineral density (BMD) at femoral head region. Isokinetic PT of hip flexors, extensors, abductors and adductors and knee flexors and extensors will be measured using Biodex System 3 Isokinetic Dynamometer. The measured outcomes will be evaluated at an angular velocity of 60°/sec in a concentric mode of muscle contraction for five successive repetitions. Isokinetic testing will be done at the Isokinetic Laboratory, Faculty of Physical therapy, Cairo University.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Cross Sectional

入排标准

年龄范围
50 Years 至 70 Years(Adult, Older Adult)
性别
Female
接受健康志愿者
否

入选标准

  • •The group of OP (n=33) has femoral BMD T-scores below -2.5 diagnosed by DEXA scan according to the WHO [8] classification of BMD in 2003,
  • •The control group has normal BMD T-scores more than -1.

排除标准

  • •There was any neurological, musculoskeletal, rheumatologic, respiratory or cardiovascular problem.
  • •They were receiving medications that result in bone loss such as corticosteroids,
  • •They had vertigo, dizziness, or any vestibular problem,
  • •They had hyperthyroidism or hyperparathyroidism. 6- They actively participate in sports activities,
  • •They underwent previous surgery (e.g; joint replacement) or history of fractures of the lower extremity.

结局指标

主要结局

isokinetic strength of hip muscles

时间窗: one month

isokinetic hip muscle stregth will be measured using Biodex system 3 Isokinetic Dynamometer

Bone mineral density

时间窗: one month

bone mineral density measured by dual energy x ray absorptiometry scan

次要结局

  • isokinetic strength of knee muscles(one month)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Azza Mohammed

Prof. Dr

Cairo University

研究点 (1)

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