NCT02109120已完成不适用
Dynamic Changes of MMP9 Concentration Cross Carotid Endarterectomy Monitoring Particulate Cerebral Embolisation
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- postoperative ischemic stroke
研究概览
简要总结
- In carotid endarterectomy(CEA) surgery, the dynamic changes of plasma MMP9 concentration cross CEA will be identified.
- And the part of patients suffered particulate cerebral embolic injury, their MMP9 level will increase in the early stage after CEA.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients enrolled had at least ≥70% unilateral or bilateral stenosis of Internal -Carotid Artery， or those who had a <70% stenosis but obvious cerebral ischema symptoms had been existed.
排除标准
- •Exclusion criteria included poor temporal window
- •Refused to cooperate with us
- •Nonatheromatous such as takayasu arteritis and fibromuscular dysplasia.
结局指标
主要结局
postoperative ischemic stroke
时间窗: 7 days after surgery
次要结局
- postoperative elevation of plasma MMP9(perioperative phage)
研究者
研究点 (1)
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