NCT01817673已完成不适用
Creatine Supplementation on Kidney Function in Resistance-trained Individuals
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- kidney function
研究概览
简要总结
There is a claim that creatine supplementation might affect kidney function, especially in those consuming a high-protein diet. The aim of this study was to investigate the effects of creatine supplementation on kidney function in resistance-trained individuals ingesting a high-protein diet.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •participation in recreational resistance training
- •consumption of a high-protein diet (≥ 1.2 g/Kg/d)
排除标准
- •vegetarian diet
- •use of creatine supplements in the past 6 months
- •chronic kidney disease
- •use of anabolic steroids.
研究组 & 干预措施
placebo (dextrose)
Placebo Comparator
20 g/d for 5 d followed by 5 g/d throughout the trial
干预措施: placebo (Dietary Supplement)
creatine
Experimental
20 g/d for 5 d followed by 5 g/d throughout the trial
干预措施: creatine (Dietary Supplement)
结局指标
主要结局
kidney function
时间窗: 3 months
as assessed by 51Cr-EDTA clearance
次要结局
- proteinuria(3 months)
- albuminuria(3 months)
- serum urea(3 months)
- serum creatinine(3 months)
研究者
Bruno Gualano
Professor
University of Sao Paulo
研究点 (1)
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