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临床试验/NCT05848414
NCT05848414已完成不适用

Short Term Outcomes in Hospitalized Patients With Liver Cirrhosis

Assiut University1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年2月7日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
100
试验地点
1
主要终点
evaluate the 90-day mortality of patients admitted with liver cirrhosis

研究概览

简要总结

This study will be conducted to assess the baseline characteristics and evaluate the 90-day mortality of patients admitted with liver cirrhosis. Also, the study will be done to identify the risk factors of 90-day mortality.

详细描述

Liver cirrhosis is the end spectrum of all chronic liver diseases characterized by advanced fibrosis, scarring, and formation of regenerative nodules leading to hepatic architectural distortion.

Liver cirrhosis is a major cause of health burden worldwide. According to the Global Burden of Disease study, liver cirrhosis caused 1.2% of global disability-adjusted life years and 2% of all deaths worldwide in 2010, the 14th leading cause of mortality.

The progress rate of compensated cirrhosis to decompensated cirrhosis is approximately 58% and once it progresses to decompensated cirrhosis, its mortality rate within 5 years becomes 85% without liver transplantation. Since the progression of cirrhosis is accelerated each time a complication recurs, the management and treatment of the complication are critical in enhancing the quality of life and the life expectancy of patients .

Post-discharge outcomes are an integral component of healthcare, as they may aid in determining the success and longevity of treatment and how clinicians approach future cases .

This study will focus on the short-term outcomes of patients hospitalized with liver cirrhosis to provide insight into methods for future healthcare interventions.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • - diagnosis of liver cirrhosis, adult (age ≥ 18 years old) and patients willing to give consent during the selected period.

排除标准

  • - Patients with ages < 18 years or patients that will be lost on follow-up will be excluded from the study.

结局指标

主要结局

evaluate the 90-day mortality of patients admitted with liver cirrhosis

时间窗: 90 days

Mortality

次要结局

  • identify the risk factors of 90-day mortalit(90 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Esraa Hassan Mohamed kotbey

Doctor

Assiut University

研究点 (1)

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