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临床试验/NCT02544386
NCT02544386终止不适用

Impact of Hemiplegia Due to Stroke on the Microarchitecture of the Bone: Evaluation Using Micro CT 3D High Resolution and by Magnetic Resonance Imaging (MRI)

Centre Hospitalier Universitaire de Saint Etienne0 个研究点目标入组 10 人开始时间: 2009年6月最近更新:
适应症

试验速览

阶段
不适用
状态
终止
入组人数
10
主要终点
Bone volume / tissue volume

研究概览

简要总结

In hemiplegic, there is very little data on the impact of neurological deficit on the microarchitecture independent of bone mineral density and composition of the bone marrow. Rare studies have shown the relationship between some micro-architectural parameters and severity of neurological deficit. There is no study in humans on the evolution of the parameters of the microarchitecture assessed by 3D micro-tomography in the early phase of the installation of neurological deficits after stroke, in terms of a bearing bone, tibia, that a non-load bearing bones, radius.

详细描述

Each patient must answer several questionnaires about their calcium intake and its ability to perform everyday tasks. They will also have 3 blood samples (15 ml each time), 3 measure of bone by 3D micro-tomography and 2 MRI examination. These examinations and sampling will take place after 30 days after stroke onset (except for MRI) and again after three months and six months after the stroke (the same day as the medical follow-up visit).

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
30 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Bone volume / tissue volume

时间窗: 90 days

Measure of Bone volume / tissue volume by the 3D CT scan

次要结局

  • Bone volume / tissue volume(1 day)
  • intraosseous fat(90 days)

研究者

申办方类型
Other
责任方
Sponsor

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