NL-OMON27391尚未招募不适用
Treatment of severe steroid-refractory acute GvHD with mesenchymal stromal cells.A phase III randomized double-blind multi-center HOVON study.
HOVON Data Center0 个研究点目标入组 150 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 150
研究概览
简要总结
/A
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Grade II-IV acute GvHD with gut and/or liver involvement, confirmed by histology of involved tissues (in case of gut and liver involvement histology of either one of these tissues is considered sufficient);
- •Non-responsive to treatment with steroids and a calcineurin-inhibitor defined as:
排除标准
- •Use of prophylactic MMF, Myfortic or other systemic treatment for acute GvHD ≤ 6 days prior to development of acute GvHD grade II-IV with gut and/or liver involvement;
- •Systemic treatment for acute GvHD other than steroids and a calcineurin inhibitor (budesonide is considered a local treatment);
研究者
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