Digital Micro-Interventions to Reduce Stigma-Driven Barriers and Improve PrEP Readiness Among People Who Use Drugs in Kazakhstan
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Mean Score Acceptability of Intervention Measure (AIM)
研究概览
简要总结
This study is a mixed-methods pilot designed to evaluate the feasibility, acceptability, and appropriateness of a brief digital micro-intervention aimed at reducing stigma-related barriers to pre-exposure prophylaxis (PrEP) engagement among people who use drugs (PWUD) in Kazakhstan. Participants will complete baseline and post-intervention surveys and receive structured informational content via Telegram or WhatsApp over approximately 2-3 weeks. The intervention focuses on addressing anticipated stigma, confidentiality concerns, and misinformation that may prevent PWUD from seeking PrEP services. No clinical procedures, medication provision, or biological specimen collection are involved.
详细描述
The proposed study has three aims:
- To refine a brief, stigma-informed digital micro-intervention designed to address structural and anticipated barriers to PrEP uptake among people who use drugs (PWUD) in Kazakhstan.
- To assess the feasibility, acceptability, and appropriateness of delivering this intervention through secure digital platforms (e.g., Telegram or WhatsApp).
- To evaluate preliminary changes in PrEP-related knowledge, perceived stigma- related barriers, and readiness to seek PrEP services following exposure to the intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Self-reported drug use within the past six months
- •HIV-negative or unknown HIV status (self-reported)
- •Not currently taking PrEP
- •Able to provide informed consent
- •Have access to a personal mobile phone capable of receiving Telegram or WhatsApp messages
排除标准
- •Are unable to provide informed consent
- •Do not have access to a mobile device for digital message delivery
- •Are currently enrolled in another PrEP behavioral intervention study
结局指标
主要结局
Mean Score Acceptability of Intervention Measure (AIM)
时间窗: Baseline and Post intervention (Week 4)
Acceptability of the intervention will be assessed using the Acceptability of Intervention Measure (AIM). It has 4-items scored on a 5-point Likert scale summed to achieve a total score. Total score range of 0-20. Higher scores indicate more acceptability.
Mean Score Intervention Appropriateness Measure (IAM)
时间窗: Baseline and Post intervention (Week 4)
The Intervention Appropriateness Measure (IAM) is a 4-item, 5-point Likert scale ( 1=Completely Disagree to 5=Completely Agree) used to evaluate the perceived fit, relevance, or compatibility of an intervention or implementation strategy. Total score range 0-20. Higher scores indicate better appropriateness.
Mean Score Feasibility of Intervention Measure (FIM)
时间窗: Baseline and Post intervention (Week 4)
Feasibility of intervention measured using Feasibility of Intervention Measure (FIM)- a 4-item instrument to assess perceived intervention feasibility. Total score 1-5 with higher scores indicating greater feasibility.
次要结局
- Change in PrEP knowledge(Baseline and Post intervention (Week 4))
- Change in perceived stigma-related barriers(Baseline and Post intervention (Week 4))
- Change in readiness to seek PrEP(Baseline and Post intervention (Week 4))
- Mean number of clicks or links accessed(Baseline and Post intervention (Week 4))
- Mean number of messages delivered(Baseline and Post intervention (Week 4))