Progressive post-resection program after pancreatic resection for malignoma and pre-cancerous lesions of the pancreas - pPRP

According to our data supervised exercise in pancreatic cancer patients and survivors may be proposed and started as soon as possible in order to improve certain aspects of QoL, since early controlled implementation seems to be safe. Also, benefits on some symptoms including physical and psychological aspects have been proved in this study. The impact on physical functioning is indeed so strong that even the small sample of this study was sufficient to demonstrate its significant effect. More data are needed to determine the optimal exercise frequency and intensity based on each patient´s training capacity or tumour stage, as a precision medicine approach is essential to address the issues of QoL. Well-designed multicentre randomized controlled trials with study populations between 20 and 1400 patients are required to examine the long-term effects of supervised and home-based exercise interventions on certain aspects of health related QoL after pancreatic cancer surgery.