A comparative study of P6 acupressure and intravenous ondansetron for prevention of postoperative nausea and vomiting following intrathecal buprenorphine
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- P6 acupressure is effective in preventing post operative nausea and vomiting following intrathecal buprenorphine
研究概览
简要总结
120 patients fulfilling the above criteria will be included after written, informed consent. they will be randomly divided into 3 groups of 40 each named A, B, and C. Group A : acupressure group, Group B: 4 mg IV ondansetron group, and group C control. All patients will receive 2.8 to 3 ml of 0.5% heavy bupivacaine + 150 mcg buprenorphine in spinal anesthesia. all will maintain their bands/ sham bands for 24 hours postop and will be observed for occurrence of PONV
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
- 盲法
- Double Blind Double Dummy
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA class I or II patients 2)Requiring orthopaedic surgery of the lower limbs under spinal anesthesia.
排除标准
- •Gastrointestinal disorders 2)Major systemic disease (ASA class III or more) 3)Obesity 4)Carpal tunnel syndrome and any deformity at the wrist 5)Known allergy to any of the study drugs 6)Contraindications to neuraxial blocks 7)On antiemetic drugs.
结局指标
主要结局
P6 acupressure is effective in preventing post operative nausea and vomiting following intrathecal buprenorphine
时间窗: intraoperative period, post operative period upto 12 hours
P6 acupressure is not effective in preventing post operative nausea and vomiting following intrathecal buprenorphine
时间窗: intraoperative period, post operative period upto 12 hours
次要结局
- any possible adverse effects of acupressure compared with ondansetron(intraoperative and postoperative period)