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临床试验/NCT01629654
NCT01629654
已完成
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Poststroke Fatigue - Developing and Testing a Program to Reduce and Cope With Fatigue

University of Aarhus1 个研究点 分布在 1 个国家目标入组 41 人2011年3月

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Cardiovascular Disease
发起方
University of Aarhus
入组人数
41
试验地点
1
主要终点
Multidimensional Fatigue Inventory 20
状态
已完成
最后更新
13年前

概览

简要总结

Fatigue is a common complaint after stroke, reported by 39-72% of patients. Poststroke fatigue is related to poor neurological recovery, low level of activities of daily living, decreased quality of life and may possibly affect the ability to return to work. Little is known about strategies addressing post-stroke fatigue and their effectiveness.

Aim: to develop, test and evaluate a health promotion program based on strategies addressing poststroke fatigue.

详细描述

Fatigue is a common complaint after stroke, reported by 39-72% of patients. It has been shown that poststroke fatigue may be related to poor neurological recovery, low level of activities of daily living and decreased quality of life. However, little is known about strategies to address poststroke fatigue and the effectiveness of such strategies. Objective The aim of the study is to develop a program based on strategies to address poststroke fatigue and to test and evaluate the program. Material and Methods Intervention Mapping is the overall approach of the study. It describes a protocol for the development of theory- and evidence-based health promotion programmes. Step 1) The program is developed based on a needs assessment. Existing knowledge about physical, psychosocial and environmental factors associated with poststroke fatigue is mapped in a literature review. Step 2) The program will be tested in a pilot study (controlled trial). In addition to conventional treatment, the patients in the intervention group will participate in the program for a period of 12 weeks. The control group will receive conventional treatment only. Step 3) Evaluation of the program: Primary outcome measure will be fatigue, measured on the Multidimensional Fatigue Inventory-20. Secondary outcome measures will be identified during the development of the program. Patients will be tested at baseline, after 3 months and after 6 months. The effect size in the pilot study will be assessed and will be used in order to estimate the required sample size for a large-scale randomized controlled trial on formally testing the efficacy of the program.

注册库
clinicaltrials.gov
开始日期
2011年3月
结束日期
2012年6月
最后更新
13年前
研究类型
Interventional
研究设计
Single Group
性别
All

研究者

责任方
Sponsor

入排标准

入选标准

  • Patients with first ever stroke
  • \> 18 year
  • Living in the area of Aarhus(intervention group) and patients living in the area of Holstebro (control group).
  • Multidimensional Fatigue Inventory-20/Generel Fatigue \>
  • The patient must be able to give informed consent
  • Walking without person support.
  • Walking aids is accepted.

排除标准

  • Neurological problems related to acute stroke(severe aphasia, decreased level of conscience or decreased attention)
  • Other neurologic or psychiatric deseases (including dementia, non treated depression, misuse of alcohol eller medicin)
  • Severe co-morbidity (including cancer, blindness or deathness)
  • Not-danish speaking.

结局指标

主要结局

Multidimensional Fatigue Inventory 20

时间窗: Change from baseline in MFI-20 at 3 and 6 months

The multidimensional Fatigue Inventory 20 is a multidimensional fatigue score covering five dimensions of fatigue: General Fatigue, Physical Fatigue, Mental Fatigue, Reduced Motivation and Activity. Pathologic Fatigue is defined as a score ≥ 12 on the General Fatigue dimension.

次要结局

  • The general self-efficacy scale(Change from baseline in the generel self-efficacy scale at 3 and 6 months)

研究点 (1)

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