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临床试验/NL-OMON41751
NL-OMON41751尚未招募不适用

Feasibility study of saliva swallowing frequency measurements using 24-hours ambulatory impedance-pH monitoring in patients with Parkinson*s disease and drooling. - 24 hr saliva swallowing frequency measurement in Parkinson*s disease.

niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 5 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
5

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational invasive

入排标准

年龄范围
18 至 99(—)

入选标准

  • Patients diagnosed with Parkinson's disease or with an atypical parkinsonism irrespective of Hoehn & Yahr stage.
  • Patients with slight to severe complaints about saliva control or drooling.
  • Patients who are able to cooperate in the protocol.

排除标准

  • Any medical treatment of drooling causing hyposalivation.
  • Suspected or confirmed pharyngeal or upper esophageal obstruction.
  • Severe coagulopathy, outside the therapeutic range when applicable.
  • Presence of any structural abnormality of the esophagus which theoretically may be associated with an increased risk of side effect or hamper the intubation. These includes peptic strictures, ulcers, tumors, varices or large diverticula.
  • Cardiac conditions such as a previous episode of bacterial endocarditis, heart valve replacement, implantable cardiac defibilator or pacemaker, or any cardiac condition in which vagal stimulation is poorly tolerated.

研究者

发起方
niversitair Medisch Centrum Sint Radboud

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