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临床试验/NCT07572500
NCT07572500撤回不适用

Minimizing Deoxygenation Events During Anesthesia With a Novel Distal Pharyngeal Airway

Stanford University0 个研究点开始时间: 2025年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
撤回

研究概览

简要总结

The goal of the study is to compare deoxygenation events during anesthesia induction and mask ventilation when using standard oral pharyngeal airways or the novel distal pharyngeal airway.

详细描述

This prospective RCT will study adult patients who are determined to be at high risk for deoxygenation events during induction of general anesthesia. The study will randomize patients for use of a novel airway device (distal pharyngeal airway) versus standard oral pharyngeal airway during general anesthetic induction and measure differences in severity and duration of desaturation (hypoxic) events. The premise is the new novel device will reduce hypoxic events, improving patient safety and reducing airway complications. This is critically important as hypoxic events can have significant consequences. Providing a device that minimizes hypoxic events could impact patient safety positively. Additional measurements will include reduction in unanticipated patient admissions from airway complications with DPA use.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patient presenting for surgery at main Stanford Hospital
  • Over 18 years old
  • ASA Class II, III, IV
  • High risk for hypoxic events during intubation based on their past medical history
  • Likelihood of obstructive sleep apnea utilizing the STOP-BANG questionnaire
  • History of diagnosed sleep apnea
  • History of difficult intubation
  • Prior need for two-handed mask ventilation
  • Requiring general anesthesia with endotracheal intubation for surgery

排除标准

  • Altered mental status
  • Anesthesia technique includes rapid sequence or modified rapid sequence intubation
  • Poorly controlled gastroesophageal reflux

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jean-Louis Horn

Professor of Anesthesiology, Perioperative and Pain Medicine

Stanford University

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