NCT01175746已完成不适用
The Effect of Nicardipine on Kidney Function During Orthognathic Surgery Under Hypotensive Anesthesia
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 46
- 主要终点
- Creatinine Clearance
研究概览
简要总结
Since nicardipine is known to protect kidney function, nicardipine infusion will result in better renal parameters measured in this study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy adult patients undergoing hypotensive anesthesia
排除标准
- •patients with any co-morbidity
研究组 & 干预措施
remifentanil
Active Comparator
干预措施: remifentanil (Drug)
nicardipine
Experimental
干预措施: Nicardipine (Drug)
结局指标
主要结局
Creatinine Clearance
时间窗: 2hr after the start of hypotensive anesthesia
Hypotensive anesthesia means that we maintain the mean blood pressure between 55 \& 65 mmHg during surgery to decrease the blood loss. The specific time point is exactly 2hr after we star to lower the blood pressure.
次要结局
未报告次要终点
研究者
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