The effect of fasting-induced insulin resistance on brown adipose tissue activity, non-shivering thermogenesis and skeletal muscle mitochondrial uncoupling. - Effect of insulin resistance on brown adipose tissue activity.

niversiteit Maastricht0 个研究点目标入组 18 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•Healthy, lean (BMI 18-25 kg/m2) adults
•Age: 18-30 years
•Male and female
•For females: use of a specific oral contraceptive (Microgynon 30 or levonorgestrel/ethinylestradiol)
•Sedentary (=< times/week or =< 3 hours/week sports)

•Cardiovascular diseases
•Hypertension (systolic/diastolic blood pressure > 140/90)
•Hypotension (systolic/diastolic blood pressure <90/60)
•Use of beta-blockers
•Asthma or other obstructive pulmonary diseases
•Diabetes Mellitus type 1 and type 2
•Elevated blood glucose levels (>5.6 mmol/l)
•Hyperthyroidism
•Participation in earlier research or medical examinations that included PET/CT scanning
•Radiation therapy due to medical treatment
•Unstable body weight (weight gain or loss >3kg in the past 2 months)
•Any known or suspected obstructive disease of the gastrointestinal tract, hypo motility disorders of the gastrointestinal tract or previous gastrointestinal surgery.

发起方