临床试验/DRKS00008943

DRKS00008943已完成未知

Obesity hypoventilation syndrome treated with non-invasive ventilation: can we switch to CPAP?

Pneumologie0 个研究点目标入组 43 人开始时间: 2015年7月29日最近更新: 2024年8月19日

适应症

试验速览

阶段: 未知
状态: 已完成
发起方: Pneumologie
入组人数: 43

研究概览研究设计入排标准研究者记录与标识符相似试验

研究概览

简要总结

暂无简介。

研究设计

研究类型: Interventional
分配方式: N/a: Single Arm Study
盲法: Open (masking not used)

入排标准

年龄范围: 18 Years 至 one（—）
性别: All

入选标准

•Stable OHS patients on BiPAP therapy for at least 3 months considered successful as determined by diurnal PaCO2 =45 mmHg and less than 20% of total sleep time with saturation <90%.
•Initial OHS diagnosis before BiPAP implementation must fulfill the conventional diagnostic criteria: coexistence of obesity (BMI =30 kg/m²) and daytime hypercapnia (PaCO2 =45 mmHg) after excluding other hypoventilation conditions.
•Age = 18 years

排除标准

•FEV1/FVC% ratio <70% plus FEV1 <50%
•OHS patients on BiPAP therapy with unstable condition (= 2 hospitalizations for acute respiratory failure in the last year)
•Daytime PaCO2 = 45mmHg despite established BiPAP therapy
•Psychological incapacity to perform questionnaires
•Refusal to participate in the study

研究者

发起方

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