Effects of Guiding Catheter on Fractional Flow Reserve and Non-Hyperemic Pressure Ratios for the Assessment of Coronary Artery Stenoses - Disengage @Rest
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Differences between FFR before and after guiding catheter disengagement
研究概览
简要总结
The DISENGAGE@rest study is a prospective registry carried out at Federico II University of Naples with the aim to evaluate the influence of the guiding catheter engagement within the coronary ostium on both FFR and non-hyperaemic pressure ratios values (such as Pd/Pa and the Resting Full-cycle Ratio -RFR), as well as the corresponding clinical impact on decision-making strategies. Consecutive patients with at least one intermediate stenosis (40%-90% by visual estimation) in any of the 3 main coronary arteries will be included.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years;
- •Patients provides informed consent;
- •Documented coronary artery disease:
- •chronic coronary syndromes
- •acute coronary syndromes presenting with at least one stenosis with indication for invasive functional assessment.
排除标准
- •Patients unable to provide informed consent;
- •Pregnant women;
- •Any contraindication to perform angiographic study or functional evaluation with pressure wire;
- •Patients with aorto-ostial stenosis
- •Target vessel diameter < 2mm
结局指标
主要结局
Differences between FFR before and after guiding catheter disengagement
时间窗: 10 minutes
Evaluate the influence of the guiding catheter engagement within the coronary ostium on FFR values.
1. Differences between NHPR before and after guiding catheter disengagement
时间窗: 10 minutes
Evaluate the influence of the guiding catheter engagement within the coronary ostium on NHPR values
次要结局
未报告次要终点
研究者
Giovanni Esposito
Full Professor of Cardiology
Federico II University