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临床试验/NCT03344198
NCT03344198已完成不适用

Effects of Combined Diet & Exercise Intervention on Cardiovascular Risk Factors in Firefighters & Civilians

University of New Hampshire2 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2018年11月25日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
200
试验地点
2
主要终点
Change in blood pressure

研究概览

简要总结

The study will explore the capacity for a lifestyle modification in firefighters to improve blood pressure, blood vessel stiffness, inflammation, and reduce oxidative stress. The study will be a pre- post-testing controlled trial with three groups. The intervention will be a weekly circuit workout program and a Mediterranean (high fruit/vegetable) diet. The groups will be firefighters with >10yrs experience, firefighters with <10yrs experience, and control Non-firefighters.

详细描述

Recent statistics from the American Heart Association (AHA) have reported that >92% of adults in the U.S. meet at least 1 metric for cardiovascular disease risk factors. In firefighters, this increased risk is especially concerning. The National Fire Protection Agency (NFPA) estimates there are around 1.3 million firefighters in the United States, 70% of which are volunteer. The prevalence of impaired cardiovascular health is higher in firefighters than in the general population and the leading line-of-duty death (LODD) cause is cardiac related. It is known that exercise and diet mitigate cardiovascular disease risk. Meeting the physical activity guidelines remains a target of ideal cardiovascular health and a major public health concern. However, the NFPA does not require volunteer fire companies to have a fitness program for their crew, and sadly less than a third of the stations actually do. And importantly, cardiovascular-related LODD remains a major issue in the firefighter population. The results could guide clinical treatment for firefighters and may therefore reduce cardiac-related LODD.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Able to Exercise

排除标准

  • More than one anti-hypertensive medication
  • More than one cholesterol medication
  • Prior Cardiac incident

结局指标

主要结局

Change in blood pressure

时间窗: Pre-Intervention (Week 0), Post-Intervention (Week 6)

Blood pressure surge response to alarm will be measured by ambulatory blood pressure monitor

次要结局

  • Change in vascular stiffness(Pre-Intervention (Week 0), Post-Intervention (Week 6))
  • Change in inflammation(Pre-Intervention (Week 0), Post-Intervention (Week 6))
  • Change in cardiopulmonary fitness(Pre-Intervention (Week 0), Post-Intervention (Week 6))
  • Change in oxidative stress(Pre-Intervention (Week 0), Post-Intervention (Week 6))
  • Change in body composition(Pre-Intervention (Week 0), Post-Intervention (Week 6))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Deborah Feairheller

Assistant Professor

California State University, San Marcos

研究点 (2)

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