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临床试验/NL-OMON38411
NL-OMON38411已完成4 期

A randomized double blind cross-over trial of the effects of low dose and high dose hydrocortisone replacement therapy on cognition, quality of life, metabolic profile and somatosensation in patients with secondary adrenal insufficiency - Hydrocortisone replacement in patients with adrenal insufficiency.

niversitair Medisch Centrum Groningen0 个研究点目标入组 63 人开始时间: 待定最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
入组人数
63

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • Patients with secondary adrenal insufficiency
  • Age >= 18 - 75 years
  • >= One year after tumor treatment with surgery and/or radiotherapy
  • On stable concomitant medications for at least six months prior to entry of study
  • Body weight 50-100 kg

排除标准

  • Inability of legal consent
  • Documented cognitive impairment
  • Drug abuse/dependence
  • History of psychiatric disorders
  • Use of anti-epileptics (e.g. carbamezapine)
  • Cushings disease
  • Type 1 or Type 2 diabetes
  • Current treatment for second malignancy

研究者

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