Does Acupressure Help Reduce Nausea and Vomiting in Palliative Care Patients?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- 1.Visual Analogue Scale of nausea measured every 6 hours.
研究概览
简要总结
Randomised controlled trial of acupressure wrist bands for hospice in-patients suffering from terminal cancer who are troubled by nausea and vomiting.
详细描述
Pilot The study will be piloted with 10 patients to ensure that the protocol is acceptable to patients and to inform a formal power calculation for a larger study. Patients will be randomized to each arm according to a randomization programme at www.randomization.com.
Arm 1 Instruction and placement of acupressure bands at the P6 acupuncture point bilaterally. This point is located 2 cun (a Chinese measurement equal to approximately 3cm) proximal to the midpoint of the transverse crease of the wrist between the tendons of palmaris longus and flexor carpi radialis.
Arm 2 Instruction and placement of sham acupressure bands P6 acupuncture point bilaterally. Sham acupressure bands have no stud to stimulate P6.
Patients may choose to have regular anti-emetics or a subcutaneous syringe driver after 24 hours if they are not happy with their level of nausea and vomiting.
- STUDY POPULATION
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Have a diagnosis of advanced cancer with an estimated prognosis of less than 1 year but more than 3 days.
- •Describe their nausea as at least moderate on a Likert scale OR at have had at least one vomit per day for the last three days.
- •Have an underlying cause for their nausea which is thought to be irreversible OR the patient has made an autonomous choice not to proceed with treatment for any potentially reversible cause (for example surgery for obstruction or drainage of ascites).
- •Can be male or female patients but must be over the age of
- •Have signed a consent form prior to entering the study.
- •If patients are taking corticosteroids the dosage should be stable for 3 days before and during the trial.
- •Be thought to be well enough to complete the 3 day trial.
排除标准
- •Arm lymphoedema.
- •Weakness, fatigue or confusion sufficient that patient is unable to take part.
- •Previous history of acupuncture/acupressure for nausea or vomiting.
- •History of Parkinsonism or Parkinsonism on examination.
- •Patients will not be enrolled if they are sharing a room with another patient taking part in the study.
结局指标
主要结局
1.Visual Analogue Scale of nausea measured every 6 hours.
次要结局
- Number of doses of PRN anti-emetics.
- Duration of perceived nausea over preceding time period.
- Number of vomits per 24 hours.
- Volume of vomit per 24 hours.
- Adverse effects of acupressure.
- Measure of whether the patient felt the intervention helped at the end of the trial.