NL-OMON53648已完成不适用
Effect of low dose galacto-oligosaccharides (GOS) on faecal gut microbiota in adult women - Denali study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 88
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Apparently healthy women (based on screening questionnaire), living in the
- •surrounding of Wageningen (+50 km )
- •- Aged between 40 - 70 year
- •- Body Mass Index (BMI) between 18,5 - 30 kg/m2
排除标准
- •- Having a gastro-intestinal disease, such as celiac disease, Crohn*s disease,
- •Ulcerative colitis, or diagnosed irritable bowel disease;
- •- Having a history of intestinal surgery that might interfere with study
- •outcomes. This does not include an appendectomy or cholecystectomy;
- •- Diagnosed with diabetes mellitus; Use of medication that may influence the
- •study results, such as laxatives, lactase preparations, metformin, antibiotics,
- •proton pomp inhibitors, antipsychotics, NSAID*s (judged by our research
- •physician);
- •- Self-perceived or diagnosed constipation;
- •- Having a food allergy to cow*s milk or being lactose intolerant;
- •- Reported slimming, medically prescribed or other diets
- •- Reported weight loss or weight gain of >5kg in the month prior to screening
- •- Use of pre-, pro- , syn- and/or postbiotics (should be stopped at least 4
- •weeks before the start of the study), or other supplements that can influence
- •the study results (to be determined by the medical investigator);
- •- History of side effects with the use of prebiotic supplements
- •- Use of antibiotic treatment less than 3 months before start of the study
- •- Pregnant or lactating (or having the wish to become pregnant during the study
- •period, self-reported);
- •- Not able to comply with study procedures;
- •- Abuse of drugs (should be stopped at least 4 weeks before the study);
- •- Alcohol intake >=7 glasses of alcoholic beverages per week, on average
- •- Participation in another clinical trial at the same time;
- •- Being an employee of the Food, Health & Consumer Research group of Wageningen
- •Food & Biobased Research or employee of FrieslandCampina R&D.
研究者
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