Biomarker and Multidisciplinary Predialysis Education in Chronic Kidney Disease Patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 8,000
- 试验地点
- 2
- 主要终点
- difference of US dollars
研究概览
简要总结
CKD is a global endemic disease with increased comorbidities and mortality. The prevalence and the incidence of the end-stage renal disease (ESRD) are extremely high in Taiwan. Early diagnosis of disease and proper management remain challenging. The aims of this study are:
- Explore risk factors associated with CKD
- Establish multidisciplinary care model for CKD patients
- Development cost-effective clinical care pathway for CKD
- Provide bio-specimen repository for future study
详细描述
CKD is a global endemic disease with increased comorbidities and mortality. The prevalence and the incidence of the end-stage renal disease (ESRD) are extremely high in Taiwan. Early diagnosis of disease and proper management remain challenging. The aims of this study are:
- Explore risk factors associated with CKD: demographic, social and genetics factors
- Establish multidisciplinary care model for CKD patients
- Development cost-effective clinical care pathway for CKD
- Provide bio-specimen repository for future study: serum, PBMC, urine and stool
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects visiting outpatient clinics of nephrology of Chang Gung Memorial Hospital
排除标准
- •Patient receiving dialysis or transplantation
- •Unwilling to participate
结局指标
主要结局
difference of US dollars
时间窗: through study completion, every 1 year
differences of US dollars of medical care (out patients and inpatients service fees) between groups
percentage (%)
时间窗: through study completion, every 1 year
percentage of patients with new CKD, starting dialysis treatments, cardiovascular event or mortality
次要结局
- fold changes of microRNA(through study completion, every 1 year)
- fold changes of proteins(through study completion, every 1 year)
研究者
I Wen Wu, MD
Principal Investigator
Chang Gung Memorial Hospital