COMPARISON OF ERECTOR SPINAE PLANE BLOCK, QUADRATUS LUMBORUM BLOCK, AND TRANSVERSUS ABDOMINIS PLANE BLOCK IN POSTOPERATIVE PAIN MANAGEMENT IN GYNECOLOGICAL ABDOMINAL SURGERIES
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- morphine consumption in the postoperative period
研究概览
简要总结
This study compares the effects of transversus abdominis plane (TAP) block, quadratus lumborum block (QLB), and erector spinae plane block (ESP) on postoperative morphine consumption, pain scores, patient satisfaction, and side effects in patients undergoing gynecological abdominal laparotomy surgeries.
详细描述
Patients will be randomly assigned into four groups using a computer-generated randomization method. According to group allocation, patients will receive the following interventions before extubation under ultrasound (US) guidance except control group:
Group E (n=20): Bilateral erector spinae plane (ESP) block will be performed with 40 ml of 0.25% bupivacaine (20 ml on each side) at the T12 level, approximately 3-4 cm laterally from the midline, in the neurofascial plane between the transverse processes and the erector spinae muscle.
Group Q (n=20): Bilateral quadratus lumborum block (QLB) will be performed with 40 ml of 0.25% bupivacaine (20 ml on each side), placed between the psoas major and quadratus lumborum muscles under US guidance, between the iliac crest and the 12th rib.
Group T (n=20): Bilateral transversus abdominis plane (TAP) block will be performed with 40 ml of 0.25% bupivacaine (20 ml on each side) in the neurofascial plane between the internal oblique and transversus abdominis muscles.
Group C (Control group, n=20): No block will be applied, only the standard intravenous patient-controlled analgesia (PCA) protocol will be used.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 69 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •aged between 18 and 69 years, with ASA 1-2 score scheduled to undergo major gynecological abdominal surgery
排除标准
- •ASA score 3 or above, patients younger than 18 or older than 69 years, patients with bleeding disorders or using anticoagulants, patients with a body mass index over 40, patients with known allergies to any drugs used in the study, and patients who could not or did not wish to use Patient-Controlled Analgesia (PCA) device
研究组 & 干预措施
Group Q
Group QLB & ESP, TAP, Control
干预措施: ESP Plane block (Procedure)
Group Q
Group QLB & ESP, TAP, Control
干预措施: TAP Block (Procedure)
Group T
Group T & ESP, QLB, Control
干预措施: ESP Plane block (Procedure)
Group T
Group T & ESP, QLB, Control
干预措施: QLB plane block (Procedure)
Group C
Group C & ESP, QLB, TAP
Group E
Group ESP & QLB, TAP, Control
干预措施: QLB plane block (Procedure)
Group E
Group ESP & QLB, TAP, Control
干预措施: TAP Block (Procedure)
Group T
Group T & ESP, QLB, Control
干预措施: No intervention (Other)
Group Q
Group QLB & ESP, TAP, Control
干预措施: No intervention (Other)
Group E
Group ESP & QLB, TAP, Control
干预措施: No intervention (Other)
结局指标
主要结局
morphine consumption in the postoperative period
时间窗: For postoperative 24 hours
Thus the primary aim of this study was to assess the morphine consumption in the postoperative period
次要结局
- pain score (VAS=0-10), patient satisfaction (0-10), the need for rescue analgesia (mg) and side effects(For postoperative 24 hours)
研究者
Hakki Unlugenc
Prof Dr
Cukurova University