Assessing the Reliability of Smooth Pursuit Across Various Neck Postures Using a Custom Ocular Motor Detection System
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Analyzied the reliability of custom-made ocular motor detectation system
研究概览
简要总结
Phase 1：System Development and Validation A custom-made eye movement detection system was developed to quantify smooth pursuit eye movements under multiplanar neck postures. The initial study established the reliability and measurement consistency of ocular motor parameters, including Gain, SPNTD, Accuracy, and Latency, in healthy individuals. The findings demonstrated acceptable-to-excellent reliability and confirmed the feasibility of assessing ocular motor performance across multiple cervical planes.
Phase 2：Clinical Application in Mechanical Neck Pain Based on the validated system developed in Phase 1, the present study investigates multidimensional oculomotor and cervical sensorimotor function in individuals with upper mechanical neck pain (MNP). By comparing MNP patients with asymptomatic controls, the study aims to identify sensitive oculomotor biomarkers associated with cervical sensorimotor dysfunction and to explore whether multi-axis ocular motor assessment provides additional clinical information beyond conventional cervical proprioception and range-of-motion measures.
详细描述
Phase 1 Reliability and Performance Evaluation of a Custom-Made Oculomotor Detection System Across Multiplanar Neck Positions
The integration of cervical proprioceptive input, visual information, and vestibular signals plays an essential role in gaze stabilization and sensorimotor control. Previous studies have suggested that alterations in cervical afferent input may influence oculomotor performance and contribute to symptoms such as dizziness and impaired visual stability. However, most conventional smooth pursuit assessments have been restricted to a single rotational axis, primarily focusing on horizontal neck torsion positions and velocity-based parameters.
To address these limitations, a custom-made oculomotor detection system was developed to quantify smooth pursuit eye movements under multiple cervical orientations. The system was designed to evaluate eye movement performance across different neck planes, including neutral posture, lateral flexion, flexion-extension, and rotational positions. Multiple ocular motor parameters were incorporated to provide a multidimensional assessment framework, including pursuit Gain, Smooth Pursuit Neck Torsion Difference (SPNTD), Accuracy, and Latency.
The primary objective of this study was to evaluate the measurement performance and reliability of the custom-made system in healthy individuals. Specifically, the study aimed to determine the consistency of ocular motor parameters across repeated measurements and to investigate whether different neck positions influence smooth pursuit tracking performance. Reliability was assessed using intraclass correlation coefficients (ICC), while differences among cervical orientations were analyzed using non-parametric statistical methods.
The findings of this study established the technical feasibility and reliability of the custom detection system and provided preliminary normative data regarding ocular motor performance under multiplanar cervical conditions. These results support the use of the system as a research and clinical assessment tool for evaluating cervical-ocular sensorimotor interactions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Screening
- 盲法
- Double (Participant, Investigator)
盲法说明
In research protocol, all neck postures were randomized, and did eye tracker recalibration before each task.
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age between 20 and 60 years.
- •No history of significant neck surgeries.
- •No history of corrective eye surgery.
- •No skeletal muscle injuries or pain in the upper or lower limbs.
- •Free from vestibular system-related disorders and neurological symptoms.
- •Participants must avoid food and drink for 3 hours before the experiment.
- •Participants should have 8 hours of sleep the night before the experiment.
排除标准
- •Any participant who has undergone vision correction surgery in the last year.
- •Any participant who has experienced significant head or neck trauma in the past year.
- •Any participant with a history of vestibular system disorders or neurological symptoms.
- •Participants who have used medications or alcohol for an extended period.
- •Participants with abnormal pain in any part of the torso.
- •Individuals suffering from claustrophobia.
研究组 & 干预措施
Health population
Used custom-made ocular motor system to adjust the neck postures of participants, to examine the reliability of data and compared the pursuit ability in three different neck motion planes, seven different neck postures.
干预措施: Smooth pursuit neck torsion test (Device)
Health population
Used custom-made ocular motor system to adjust the neck postures of participants, to examine the reliability of data and compared the pursuit ability in three different neck motion planes, seven different neck postures.
干预措施: Visual Analogue Scale (Other)
Health population
Used custom-made ocular motor system to adjust the neck postures of participants, to examine the reliability of data and compared the pursuit ability in three different neck motion planes, seven different neck postures.
干预措施: Craniovertebral Angle (Device)
Health population
Used custom-made ocular motor system to adjust the neck postures of participants, to examine the reliability of data and compared the pursuit ability in three different neck motion planes, seven different neck postures.
干预措施: Joint Position Error (Device)
Upper Mechanical Neck Pain
Participants with upper mechanical neck pain will undergo multidimensional cervical sensorimotor and oculomotor assessments. Evaluations include cervical range of motion, joint position error testing, and smooth pursuit eye movement tasks performed under multiple neck orientations to investigate cervical-ocular sensorimotor function
干预措施: Smooth pursuit neck torsion test (Device)
Upper Mechanical Neck Pain
Participants with upper mechanical neck pain will undergo multidimensional cervical sensorimotor and oculomotor assessments. Evaluations include cervical range of motion, joint position error testing, and smooth pursuit eye movement tasks performed under multiple neck orientations to investigate cervical-ocular sensorimotor function
干预措施: Visual Analogue Scale (Other)
Upper Mechanical Neck Pain
Participants with upper mechanical neck pain will undergo multidimensional cervical sensorimotor and oculomotor assessments. Evaluations include cervical range of motion, joint position error testing, and smooth pursuit eye movement tasks performed under multiple neck orientations to investigate cervical-ocular sensorimotor function
干预措施: Craniovertebral Angle (Device)
Upper Mechanical Neck Pain
Participants with upper mechanical neck pain will undergo multidimensional cervical sensorimotor and oculomotor assessments. Evaluations include cervical range of motion, joint position error testing, and smooth pursuit eye movement tasks performed under multiple neck orientations to investigate cervical-ocular sensorimotor function
干预措施: Joint Position Error (Device)
结局指标
主要结局
Analyzied the reliability of custom-made ocular motor detectation system
时间窗: From enrollment to the end of research at 1 day.
The custom-made system would output four parameters in this study. Used Intraclass correlation coefficient (ICC) to examine the reliability of pursuit parameters.
次要结局
- Examine the pursuit ability in seven different neck postures.(From enrollment to the end of treatment at 1 day)
研究者
Jeng-Heng Lin
Master
Kaohsiung Medical University