ACTRN12611000666921尚未招募3 期
In patients receiving docetaxel for early stage breast cancer who experience taxane associated acute pain syndrome is gabapentin better than placebo for reducing pain?
Sunshine Coast Cancer Centre, Nambour General Hospital0 个研究点目标入组 126 人开始时间: 2011年7月1日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 126
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- Female
入选标准
- •Patients with histologically confirmed adenocarcinoma of the breast who have completed definitive surgery and meet the following criteria
- •1.Planned and agreeable to treatment with docetaxel 100mg/m2 3 weekly as part of the regimen FEC-
- •D for early stage breast cancer
- •2.Adequate organ function for the planned chemotherapy
- •3.Creatinine clearance of >50ml/min by estimated glomerular filtraiton rate
- •4.Ages 18 years or over
- •5.Able to give informed consent
- •6.Received no prior taxane chemotherapy
排除标准
- •1.Score of 4 or more for ‘pain on average over the last 24 hours” on day prior to cycle 1 docetaxel (i.e.
- •pre existing pain)
- •2.Regular use of analgesia (other than for post operative pain)
- •3.Epilepsy or seizure disorder
- •4.Metastatic disease
研究者
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