FURAZOLIDONE VS CIPROFLOXACIN IN THE TREATMENT OF MILD OR MODERATE DYSENTERY IN CHILDREN UNDER 5 YEARS OLD: A SINGLE BLIND, RANDOMIZED CLINICAL TRIAL OF NON-INFERIORITY.

IVERSIDAD PERUANA CAYETANO HEREDIA, Instituto Nacional de Salud del Niño,0 个研究点目标入组 7 人开始时间: 2011年12月22日最近更新: 2023年9月4日

试验速览

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•EVERY PATIENT TO BE INCLUDED IN THIS STUDY IS OVER 12 MONTHS AND UNDER 5 YEARS (60 MONTHS) OF AGE, WITH THIS PICTURE OF MILD DYSENTERY (AQUEOUS DIARRHEA WITH FEVER AND PRESENCE OF RED CELLS AND PLATELETS> 50 FOR FIELD) OR MODERATE DYSENTERY 72hrs OR LESS DURATION AND GO TO BE ATTENDED IN HOSPITALS SELECTED FOR THE STUDY.

•CHILDREN WITH A PREVIOUS DIAGNOSIS OF CONDITIONS TO BE CONSIDERED CONTRAINDICATIONS FOR TREATMENT WITH FURAZOLIDONE, SUCH AS LACK OF GLUCOSE 6 PHOSPHATE DEHYDROGENASE, HEMOLYTIC ANEMIA RELATED TO G6PD AND KINASE PYRUVATE DEFICIENCY.
•CHILDREN COMORBIDITIES BACKGROUND AFFECTING THE IMMUNE STATE AND THEN THE CLINIC (INFECTION WITH HIV, AIDS; CHRONIC DISEASES: LIVER, KIDNEY, HEART, KIDNEY FAILURE, SEVERE MALNUTRITION).
•CHILDREN KNOW THAT HAS RECEIVED DIPHENOXYLATE HYDROCHLORIDE THERAPY WITH ATROPINE OR LOPERAMIDE, BECAUSE OF THE RISK OF EXTENDING DISEASE.
•CHILDREN WITH PRIOR ALLERGIC OR HYPERSENSITIVITY TO FLUOROQUINOLONES OR OTHER DERIVATIVES OF QUINOLONES.
•CHILDREN WITH TENDINITIS BACKGROUND OR BREACH OF TENDON, CENTRAL NERVOUS SYSTEM DISORDERS INCLUDING CEREBRAL ATHEROSCLEROSIS, EPILEPSY, OR OTHER FACTORS THAT PREDISPOSE TO SEIZURE.
•CHILDREN THAT HAVE RECEIVED ANY DOSE OF ANTIBIOTICS IN THE LAST 72 HOURS DURING THE CURRENT CLINICAL CONDITION.
•PATIENTS WHOSE PARENTS refuse to PARTICIPATE IN THE STUDY OR NOT SIGN THE INFORMED CONSENT.

发起方

IVERSIDAD PERUANA CAYETANO HEREDIA, Instituto Nacional de Salud del Niño,