JPRN-UMIN000036471已完成2 期
Study of the effect of sublingual immunotherapy for Japanese cedar pollinosis and the change of immunoglobulin in blood - Study of sublingual immunotherapy of Japanese cedar
ippon Medical School Musashi Kosugi Hospital0 个研究点目标入组 29 人开始时间: 2019年4月12日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 29
研究概览
简要总结
In the Complete and Poor response group, We compared the changes in the serum cytokines and immunoglobulins levels. There were no changes in the IgG4, IgE, IL-5, IL-10, IFN-g and TGF-b1 levels from January to June in either group. The levels of IL-2 and GM-CSF remained below the limit of detection. The IL-12p70 and VEGF leveis in January, March, and June were slightly higher in the Complete response group. The IL-17 levels in June were significantly higher in the Complete response group.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 12years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •Patients who are negative for Japanese cedar specific antibody in blood exam
研究者
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