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临床试验/NCT06135519
NCT06135519已完成不适用

Dermogenesis With Mesenchymal Stem Cells: A Fabulous Remedy For Post Acne Depressed Spots

King Edward Medical University2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2023年7月23日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
2
主要终点
Dermal thickness

研究概览

简要总结

Dermogenesis With Mesenchymal Stem Cells in treating Post Acne Depressed Spots

详细描述

management at two different stages of the course of the disease. First one at the stage of active disease which needs cleansers, antibiotics, retinoids, anti inflammatory agents and hormonal manipulation. Once active disease is over, patients report to clinician with depressed spots which are caused by localized dermal disruption and fat atrophy post inflammation or spontaneous epithelial rupture or scratching by the patient. These acne spots are hard to treat due to many reasons. Firstly, excision is difficult as size of most of them is small and they are in a large in number. Secondly, filling with and without subcision is not adequately addressing the deformity. Currently, a combination of filling with synthetic filler or fat and resurfacing by peeling, LASER or dermabrasion is in practice. In-spite of all, a treatment is still required to address post acne spots (Ice Spec Spots) adequately.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
— 至 50 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Acne spots

排除标准

  • Active acne

研究组 & 干预措施

Mesenchymal stem cells

Experimental

Mesenchymal Stem Cells taken from adipose tissue will be used

干预措施: Autologous Mesenchymal stem cells injection (Procedure)

Homogenized fat

Experimental

Adipose tissue will be harvested and used

干预措施: Homogenized fat injection (Procedure)

结局指标

主要结局

Dermal thickness

时间窗: 3 months

on microscopy of biopsy section

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Afzaal Bajwa

Assistant Professor

King Edward Medical University

研究点 (2)

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