Prevalence and Characteristics of Coronary Atherosclerosis in Stroke Patients Using Coronary CT Angiography
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,657
- 试验地点
- 1
- 主要终点
- MACE (Major Adverse Cardiac Event)
研究概览
简要总结
This study is to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of coronary atherosclerosis in stroke patients with coronary CT angiography.
详细描述
Stroke and coronary artery disease (CAD) share common risk factors and pathological mechanisms. CAD is an important cause of death in patients with stroke.
Currently, coronary CT angiography (CCTA) is very useful non-invasive tool for detection of CAD and plaque analysis.
Therefore, the investigators aimed to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of CAD in stroke patients through follow-up (more than 5 years) using CCTA.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
入排标准
- 年龄范围
- 30 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute stroke patients who diagnosed by clinical and brain MR imaging
- •Who performed coronary CT angiography within 3 months after acute stroke
排除标准
- •intracranial hemorrhage including intracerebral, subdural or subarachnoid hemorrhage
- •brain tumor
- •Previous myocardial infarction
- •Previously performed percutaneous coronary intervention (PCI), coronary artery bypass graft (CABG) or other cardiac surgery
- •Insufficient medical record
- •Poor image quality of CCTA scan
结局指标
主要结局
MACE (Major Adverse Cardiac Event)
时间窗: Participants will be followed until June. 2015, an expeded average of 5 years
MACE was included as follows: 1) all-cause mortality, 2) myocardial infarction, 3) unstable angina requiring hospitalization
次要结局
- Any cardiac events(Participants will be followed until June. 2015, an expeded average of 5 years)