CTIS2024-512863-30-00进行中（未招募）1 期
Deciphering B and T cell Co-stimulation for the Targeted Treatment of IgG4-Related Disease
Ospedale San Raffaele S.r.l.0 个研究点目标入组 32 人开始时间: 2024年3月29日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 32
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 年龄范围
- 18 至 65+（—）
- 性别
- All
入选标准
- •Male or female subjects of legal age and able to provide informed consent, Patients with active IgG4-related disease naive to therapy or relapsing with an IgG4- RD RI > 2, Achievement of the 2019 ACR/EULAR Classification Criteria of IgG4-related disease.
排除标准
- •Malignancy within 5 years, Serum creatinine > 2.0 mg/dL at the time of randomisation., Positive pregnancy test at screening or during the study, or breast feeding, Subjects who do not agree to use methods of contraception., Chronic or history of recurrent infections over 6 months prior to screening, Evidence of severe active liver disease unrelated to IgG4RD, Concomitant uncontrolled disease that would interfere with the study procedures, Positive HIV, HBV, HCV serology, Positive quantiferon test, Inability to be tapered of glucocorticoid therapy by 8 weeks post randomisation, Prior use of B cell depleting agents within 6 months of enrolment, Leukopenia, neutropenia, thrombocytopenia, or anemia
研究者
相似试验
进行中（未招募）
1 期
Abatacept for therapy of IgG4-related diseaseIgG4-related diseaseMedDRA version: 21.1Level: LLTClassification code 10071569Term: Immunoglobulin G4 related sclerosing diseaseSystem Organ Class: 100000004859EUCTR2022-003916-10-ITOSPEDALE SAN RAFFAELE32
尚未招募
不适用
The role of B and T cells in ITPITP1003553410003816Immune ThrombocytopeniaNL-OMON52114eids Universitair Medisch Centrum40
招募中
不适用
Characterising the immune infiltrate of B and T cell dominated skin diseases to improve therapeutic optionsL63.0L63.1L63.2L63.8Alopecia (capitis) totalisAlopecia universalisOphiasisOther alopecia areataDRKS00034344Medizinische Universität Wien40
尚未招募
Unknown
Assessment of immune response in Long COVID patientsCTRI/2024/01/061149Dr D Y Patil Vidyapeeth (Deemed to be University) Pune
进行中（未招募）
1 期
B cell therapy followed by T cell therapy to achieve immune tolerance in rheumatoid arthritis with ACPA antiboidies (TOLERA): an unblinded clinical trial in one centre with random assignment to treatment groups in adult patients who failed methotrexate therapyActive rheumatoid arthritis with ACPA antibodies failing methotrexateMedDRA version: 23.1Level: PTClassification code 10039073Term: Rheumatoid arthritisSystem Organ Class: 10028395 - Musculoskeletal and connective tissue disordersEUCTR2018-003877-91-DEniversitätsklinikum Erlangen20