A Randomized Control Trial to Compare Efficacy of Ultrasound - Guided Mandibular Nerve Block Performed Postoperatively with Preemptive Block in Mandibular Surgeries
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Duration of postoperative analgesia
研究概览
简要总结
Patients posted for mandibular fracture fixation surgeries will be included in the study. The patients will be randomly divided into two groups. Group A will receive mandibular nerve block after anaesthesia induction and endotracheal intubation and prior to surgical incision. Group B patients will receive mandibular nerve block at the end of surgery. Both the blocks will be performed with the aid of ultrasound and using Ropivacaine 0.5% 10ml.
The general anaesthesia will be standardized in both the groups. At the end of sugery, the patient will be put on patient controlled analgesia (PCA) using morphine with bolus of 1mg and lockout interval of 10 minutes.
The duration of postoperative analgesia, consumption of morphine in PCA and haemodynamic parameters will be obseved in both the groups and compared. Descriptive statics ( mean , standard deviation, and frequency ) will be included . to compare quantitive data , chi-square test was used . the results will be expressed in 95% confidence interval . a valve of p<0.05 will be considered to be statistically significant.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with ASA Physical Status I and II posted for fractures of mandible.
排除标准
- •All patients with ASA Physical Status III and above
- •Patients who refuse to participate in the study
- •Patients who are allergic to amide local anaesthetics
- •Patients who are pregnant
- •Patients with chronic cardiac, renal or hepatic condition
- •Patients with coagulation abnormalities.
结局指标
主要结局
Duration of postoperative analgesia
时间窗: within 24 hours of surgery
次要结局
- Haemodynamic parameters(The heart rate,and blood pressure intraoperatively will be observed.)
- Morphine consumption(The total consumption of morphine in the first 24 hours in PCA pump will be recorded)