Prognostic Value of Surem TRAF3IP2 Level in Patients With Acute Myocardial Infarction
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- MACEs (major adverse cardiac events)
研究概览
简要总结
To evaluate the prognostic value of surem TRAF3IP2 levels in patients with acute myocardial infarction
详细描述
Previous study had concluded that TRAF3IP2 plays a causal role in atherosclerotic plaque development and vulnerability in mice. However, no human data was available. In the present study, patients diagnosed with acute myocardial infarction who receive coronary angiography will be enrolled. Their surem TRAF3IP2 levels will be tested using ELASA. The association of surem TRAF3IP2 levels with the major adverse cardiac events will be evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with acute myocardial infarction
- •patients received coronary angiography
- •invasive management within 72 h of hospital admission
排除标准
- •NYHA III-IV
- •malignant tumor
- •acute infection
- •thyroid dysfunction
- •Life expectancy of b1 y
- •Unsuitable for PCI
结局指标
主要结局
MACEs (major adverse cardiac events)
时间窗: 1 year
MACEs were defined as a composite of cardiac death, hospitalization for myocardial infarction or heart failure
次要结局
- cardiac death(1 year)
- hospitalization for myocardial infarction or heart failure(1 year)
研究者
Jin Geng
associate doctor
Nanjing Medical University