Evaluation of Lower Limb Angiosome Perfusion and Oxygenation Using Thermal and Hyperspectral Imaging
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Perfusion in lower limb angiosomes assessed by thermal imaging
研究概览
简要总结
Assessment of a novel diagnostic method for screening and diagnosing chronic limb-threatening ischemia (CLTI). Using hyperspectral and thermal imaging, the perfusion and oxygenation in the lower limbs will be studied in healthy and unhealthy individuals.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •for CLTI patients age >50
- •for age control group age >50 and not diagnosed with cardiovascular diseases. 0.9 < ABI < 1.3
- •for healthy group 18 <= age <= 50 and no history of cardiovascular disease
- •volunteering for study
排除标准
- •inability to give informed consent
结局指标
主要结局
Perfusion in lower limb angiosomes assessed by thermal imaging
时间窗: 45 minutes during the procedure starting from the first measurement and ending after the last measurement
Thermal imaging will be used to assess the perfusion in the lower limbs. The lower limb can be divided into six angiosomes, which can then be used to assess thermal patterns. Healthy and unhealthy feet will present with different thermal patterns and other changes in thermographs.
Oxygenation in lower limb angiosomes assessed by hyperspectral imaging.
时间窗: 45 minutes during the procedure starting from the first measurement and ending after the last measurement
Hyperspectral imaging can be used in the assessment of oxygenation in the lower limb angiosomes. Based on hyperspectral imaging, oxygenation maps can be generated and then analyzed. Differences between the oxygenation maps of healthy and unhealthy patients will be established.
次要结局
未报告次要终点
研究者
Niku Oksala
Prof, MD, PhD, DSc
Tampere University