NCT01916148Available不适用
Expanded Access Use of 18F-L-Fluoro-DOPA PET/CT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic Hypoglycemia
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- Available
- 试验地点
- 1
研究概览
简要总结
This purpose of this study is to determine the ability of an 18F-fluoro-L-dihydroxyphenylalanine (18F-DOPA) PET (Positron Emission Tomography) scan to detect a focal lesion of hyperinsulinism and determine the location in patients with congenital hyperinsulinism, Beckwith Wiedemann Syndrome and suspected insulinoma. Safety data will be collected.
详细描述
Patients with hyperinsulinemic hypoglycemia are at risk for neurological damage due to hypoglycemia. Early surgical intervention can be preventative. F-DOPA PET may be able to detect of a focal lesion prior to surgical intervention and be used during surgical planning to guide the surgical procedure.
研究设计
- 研究类型
- Expanded Access
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects of any age with hyperinsulinemic hypoglycemia, diagnosed by a fasting test and/or response to glucagon stimulation.
- •Subjects who are eligible for pancreatic surgery regardless of prior pancreatic surgery
排除标准
- •Pregnant or lactating females
- •Any other major illness or condition that in the investigator's judgment will substantially increase the risk associated with the subject's participation in this study
- •Subjects who are not a candidate for pancreatic surgery
研究者
Lisa States
Principal Investigator
Children's Hospital of Philadelphia
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Application of 18F-FDOPA PET in Research of the Association Between HCV Infection and Parkinson's Disease.Hepatitis CNCT04618679National Taiwan University Hospital100
已完成
不适用
Early Interim 18F-FDG-PET and 18F-FLT-PET for Predicting Treatment Response and Survival in Metastatic Breast CancerMetastatic Breast CancerNCT04411966Chang Gung Memorial Hospital32
招募中
2 期
FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade GliomaGlioma, MalignantNCT06172595Singapore General Hospital22
No Longer Available
不适用
F18 DCFPyL PET/CT in Imaging Participants With Recurrent Prostate CancerProstate AdenocarcinomaPSA Level Greater Than 0.2PSA Level Greater Than or Equal to TwoPSA ProgressionRecurrent Prostate CarcinomaNCT03501940Andrei Iagaru
已完成
不适用
PET Scans in Diagnosing Primary or Recurrent Cervical Cancer in Patients Who Are Undergoing SurgeryCervical CancerNCT00003429Memorial Sloan Kettering Cancer Center