Study of Access Flow ,Access Recirculation of Arteriovenous Fistula and the Relationship With Cardiac Function
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- to access the chang of the fistula blood flow in HD patients using Ultrasound Dilution method
研究概览
简要总结
A prospective longitudinal surveillance for a period of 2 months. Sample - identify suitable Chronic Kidney Disease (CKD) patients who undergo HD with functioning AVF. Participants at various age range and both sexes are recruited to observe their access flow, access recirculation and cardiac function and assess their relationship.
详细描述
All patients recruited who met the inclusion criteria were investigated access flow, access recirculation and cardiac function(including cardiac output,cardiac index,central blood volume,et al).Measurement time is the beginning of HD session (first 30min to 1 hr),Middle of HD session (optional),and the end of the HD session (1hr to 30 min prior to end of session). The follow-up duration is 6 months and 12 months.Repeat the assessment at the above time points.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 16 Years 至 75 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergo HD with native AVF
- •AF of AVF between 300ml/min and 1800ml/min
排除标准
- •Patients whose AVF developed Access Recirculation (AR) which cannot be resolved at the time of measurement
- •Patients developed access or systemic infection during the study period
结局指标
主要结局
to access the chang of the fistula blood flow in HD patients using Ultrasound Dilution method
时间窗: Change of the fistula blood flow from baseline to 6 months
次要结局
- Changes of the Oxygen delivery ( Adequacy of hemoglobin level to Epoetin) during the course of hemodialysis therapy(from baseline to 6 months)
- Changes of the Cardiac Index (CI) during the course of hemodialysis therapy(from baseline to 6 months)
研究者
Xue Qing Yu
Director
Sun Yat-sen University