Noninvasive Brain Stimulation for Stroke Improvement
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 发起方
- 入组人数
- 200
- 试验地点
- 2
- 主要终点
- change in function before/after tDCS
研究概览
简要总结
Noninvasive brain stimulations will be used in acute and chronic stroke patients to improve a variety of functions.
详细描述
Noninvasive brain stimulations (NIBS) will be used in acute and chronic stroke patients to improve a variety of functions such as motor functions, cognitive functions, ...
NIBS will be applied in a placebo-controlled, double-blind, randomised fashion. Behavioural data will be collected before and after NIBS, as well as brain functional imaging data.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •stroke with at least slight deficit
排除标准
- •contraindication to tDCS and/or to fMRI
- •presence of metal in the head
- •unability to understand / complete behavioural tasks
- •chronic intake of alcohol or recreative drugs
- •major health condition
- •presence of pacemaker
- •pregnancy
结局指标
主要结局
change in function before/after tDCS
时间窗: Before intervention, immediately after intervention, 10-20-30-40-50-60 min after intervention; long-term after intervention : 1-2-3-4 weeks, 2-3-4-5-6-7-8-9-10-11-12 months
any brain function impaired by stroke
次要结局
- change in neuroimaging and neurophysiological before/after tDCS(Before intervention, immediately after intervention, 10-20-30-40-50-60 min after intervention; long-term after intervention : 1-2-3-4 weeks, 2-3-4-5-6-7-8-9-10-11-12 months)
研究者
Pr Yves Vandermeeren, MD, PhD
Professor, MD, PhD
University Hospital of Mont-Godinne