NCT00208858已完成2 期
Nicotine Craving: Neural Correlates of Treatment Effect - A Pilot Study
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 试验地点
- 2
研究概览
简要总结
The purpose of this study is to gather pilot data to determine feasibility of and guide the development of a larger clinical trial investigating the effects of topiramate as an adjunct to nicotine replacement therapy and behavioral counseling in smoking cessation treatment. It is hypothesized that topiramate will decrease nicotine craving and result in improved outcomes for smoking cessation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Male, between ages of 18-55
- •Meets DSM-IV criteria for nicotine dependence
- •Smoke at least 20 cigarettes per day
- •Motivated to quit smoking
排除标准
- •Serious or unstable medical conditions
- •Current psychiatric disorder requiring medication or treatment
- •Taking medication that create risk of interaction with study drug
- •Current participation in another smoking cessation treatment
研究者
Karen Drexler
Asc Professor/Director, Substance Abuse Treatment
Emory University
研究点 (2)
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